Chronic administration of a leupeptin-derived calpain inhibitor fails to ameliorate severe muscle pathology in a canine model of Duchenne muscular dystrophy

Calpains likely play a role in the pathogenesis of Duchenne muscular dystrophy (DMD).Accordingly, calpain inhibition may provide therapeutic benefit to DMD patients.In the present study, we sought to fp9550bk measure benefit from administration of a novel calpain inhibitor, C101, in a canine muscular dystrophy model.Specifically, we tested the hypo

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Widespread establishment of adventive populations of Leptopilina japonica (Hymenoptera, Figitidae) in North America and development of a multiplex PCR assay to identify key parasitoids of Drosophila suzukii (Diptera, Drosophilidae)

In recent years, there has been an increase in the adventive establishment and spread of parasitoid wasps outside of their native range.However, lack of taxonomic tools can hinder the efficient screening of field-collected samples to document the establishment and range expansion of parasitoids on continent-wide geographic scales.Here we report tha

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Current advances in molecular subtyping using multilocus variable number of tandem repeat analysis of Salmonella Enteritidis and Salmonella Typhimurium in Egyptian chickens

Aim: This study aimed to characterize the genetic diversity, evolutionary level, and prevalence of genotypes of common isolates of Salmonella (Salmonella Enteritidis and Salmonella Typhimurium).Using one of the most advanced chainsaw file molecular recognition techniques, multilocus variable number of tandem repeat analysis (MLVA), we characterized

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Vision-Text Cross-Modal Fusion for Accurate Video Captioning

In this paper, we introduce a novel end-to-end multimodal video captioning framework based on cross-modal fusion of visual and textual data.The proposed approach integrates a modality-attention module, which captures the visual-textual inter-model relationships using cross-correlation.Further, we integrate temporal attention into the features obtai

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